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Bazedoxifene/conjugated estrogens

Bazedoxifene/conjugated estrogens

Bazedoxifene/conjugated estrogens, sold under the brand name Duavee in the US and Duavive in the EU, is a fixed-dose combination medication for the treatment of menopause symptoms and postmenopausal osteoporosis.[4][5][6] It contains the selective estrogen receptor modulator bazedoxifene and conjugated estrogens. It is taken by mouth.

Bazedoxifene/conjugated estrogens
Combination of
BazedoxifeneSelective estrogen receptor modulator
Conjugated estrogensEstrogen
Clinical data
Trade namesDuavee, Duavive
AHFS/Drugs.comProfessional Drug Facts
License data
Routes of
By mouth
ATC code
Legal status
Legal status
  • US: ℞-only [2]
  • EU: Rx-only [3]
  • In general: ℞ (Prescription only)
CAS Number
  • None

The combination was approved for medical use in the United States in October 2013,[7] and in the European Union in December 2014.[3]

See also


  1. "Bazedoxifene / conjugated estrogens (Duavee) Use During Pregnancy". 16 February 2019. Retrieved 23 June 2020.
  2. "Duavee- conjugated estrogens/bazedoxifene tablet, film coated". DailyMed. 16 July 2021. Retrieved 21 February 2022.
  3. "Duavive EPAR". European Medicines Agency (EMA). Retrieved 10 June 2020.
  4. "Duavee. Generic Name: conjugated estrogens and bazedoxifene tablets".
  5. Palacios S, Mejía Ríos A (February 2015). "Bazedoxifene/conjugated estrogens combination for the treatment of the vasomotor symptoms associated with menopause and for prevention of osteoporosis in postmenopausal women". Drugs of Today (Barcelona, Spain : 1998). 51 (2): 107–16. doi:10.1358/dot.2015.51.2.2281023. PMID 25756066.
  6. Lello S, Capozzi A, Scambia G (2017). "The Tissue-Selective Estrogen Complex (Bazedoxifene/Conjugated Estrogens) for the Treatment of Menopause". International Journal of Endocrinology. 2017: 5064725. doi:10.1155/2017/5064725. PMC 5735652. PMID 29358948.
  7. "Drug Approval Package: Duavee (conjugated estrogens and bazedoxifene) NDA #022247". U.S. Food and Drug Administration (FDA). 7 October 2013. Retrieved 23 June 2020.

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