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Caprine alphaherpesvirus 1

Caprine alphaherpesvirus 1

Caprine alphaherpesvirus 1 (CpHV-1) is a species of virus known to infect goats worldwide. It has been shown to produce systemic and respiratory symptoms in kids and to cause abortions in adult goats.[1]

Caprine alphaherpesvirus 1
Virus classification
(unranked): Virus
Realm: Duplodnaviria
Kingdom: Heunggongvirae
Phylum: Peploviricota
Class: Herviviricetes
Order: Herpesvirales
Family: Herpesviridae
Genus: Varicellovirus
Caprine alphaherpesvirus 1

The virus is in the genus Varicellovirus, subfamily Alphaherpesvirinae, family Herpesviridae, and order Herpesvirales.[2]

It is less studied than some of the other ruminant viruses in the genus Varicellovirus including Bovine alphaherpesvirus 1 (BoHV-1), and research conflicts about its level of species specificity and its ability to cause bovine infection and illness.[3][4][5]  Like many other members of its genus, CpHV-1 has been shown to replicate in the respiratory tract and to cause latent infections.[1]  There is not currently a vaccine.[6]


  1. Martins, Bruno; Ebling, Rafael C.; Martins, Mathias; Diel, Diego G.; Weiblen, Rudi; Flores, Eduardo F. (2019-11-01). "Antigenic relationships between Caprine alphaherpesvirus 1 (CpHV-1) and Bovine alphaherpesvirus 1 (BoHV-1) and experimental CpHV-1 infection of kids and calves". Microbial Pathogenesis. 136: 103663. doi:10.1016/j.micpath.2019.103663. ISSN 0882-4010. PMID 31404631.
  2. "ICTV Master Species List 2018b.v2". International Committee on Taxonomy of Viruses (ICTV). Retrieved 19 June 2019.
  3. Hay, John; Ruyechan, William T. (2007), Arvin, Ann; Campadelli-Fiume, Gabriella; Mocarski, Edward; Moore, Patrick S. (eds.), "Alphaherpesvirus DNA replication", Human Herpesviruses: Biology, Therapy, and Immunoprophylaxis, Cambridge University Press, ISBN 978-0-521-82714-0, PMID 21348073, retrieved 2020-06-09
  4. Azab, Walid; Dayaram, Anisha; Greenwood, Alex D.; Osterrieder, Nikolaus (2018-09-28). "How Host Specific Are Herpesviruses? Lessons from Herpesviruses Infecting Wild and Endangered Mammals". Annual Review of Virology. 5 (1): 53–68. doi:10.1146/annurev-virology-092917-043227. ISSN 2327-056X. PMID 30052491. S2CID 51726438.
  5. Thiry, Julien; Keuser, Véronique; Muylkens, Benoît; Meurens, François; Gogev, Sacha; Vanderplasschen, Alain; Thiry, Etienne (March 2006). "Ruminant alphaherpesviruses related to bovine herpesvirus 1". Veterinary Research. 37 (2): 169–190. doi:10.1051/vetres:2005052. ISSN 0928-4249. PMID 16472518.
  6. "Vaccines". Retrieved 2020-06-09.

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